ERK1 anticorps (pThr197, pThr202)

N° du produit ABIN744143

L’anticorps Lapin Polyclonal anti-ERK1 a été validé pour WB, ELISA, IHC (p), IF (p), IF (cc) et IHC (fro). Il convient pour détecter ERK1 dans des échantillons de Humain, Souris et Porc. Il y a 4+ publications disponibles.

Aperçu rapide pour ERK1 anticorps (pThr197, pThr202) (ABIN744143)

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Reactivité: Humain, Souris, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ERK1 anticorps

Épitope: pThr197, pThr202

Réactivité croisée: Humain, Souris, Porc

Homologie: Rat,Dog,Cow,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human ERK1 around the phosphorylation site of Thr197/Thr202

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ERK1 (ABIN744143)

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Chu, Zhao, Feng, Zhang, Liu, Cheng, Li, Shen, Cao, Li, Min: "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." dans: Molecular and cellular endocrinology, Vol. 454, pp. 77-86, (2017) (PubMed).

Qu, Wu, Wu, Ji, Qiang, Jiang, Jiang, Ding: "Exosomal miR-665 as a novel minimally invasive biomarker for hepatocellular carcinoma diagnosis and prognosis." dans: Oncotarget, Vol. 8, Issue 46, pp. 80666-80678, (2017) (PubMed).

Zhao, Zhang, Liu, Zhang, Hao, Li, Chen, Shen, Tang, Min, Meng, Wang, Yi, Zhang: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." dans: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).

Détails sur ERK1

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Autre désignation: ERK1 +

Sujet:

Synonyms: ERK 1, ERK 2, ERK-2, ERK1, ERK2, ERT1, ERT2, Extracellular signal regulated kinase 1, Extracellular signal regulated kinase 1, Extracellular signal regulated kinase 2, Extracellular signal regulated kinase 2, Extracellular signal-regulated kinase 2, HS44KDAP, HUMKER1A, Insulin stimulated MAP2 kinase, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAP kinase isoform p44, MAPK 1, MAPK 2, MAPK1, MAPK2, MGC20180, Microtubule associated protein 2 kinase, Mitogen activated protein kinase 1, Mitogen activated protein kinase 1, Mitogen activated protein kinase 2, Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, MK01_MOUSE, p38, p40, p41, p41mapk, p42 MAPK, p42-MAPK, p42MAPK, p42MAPK, p44 ERK1, p44 MAPK, p44ERK1, p44ERK1, p44MAPK, p44MAPK, PRKM 1, PRKM 1, PRKM 2, PRKM 2, PRKM1, PRKM2, Protein kinase mitogen activated 1, Protein kinase mitogen activated 1, Protein kinase mitogen activated 2, Protein kinase mitogen activated 2, Protein tyrosine kinas.

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

ID gène: 5595

Pathways: Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins